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The 35 Best Face Serums, According to Dermatologists and Editor Testing

We’ve got every skin concern covered.

Audrey Noble, Claire Sullivan, Adam Mansuroglu

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December 27, 2022, 2:33pm

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The Best Face Serums

Courtesy of Skinceuticals, Dr. Barbara Sturm, and La Roche-Posay

If you purchase an independently reviewed product or service through a link on our website, WWD may receive an affiliate commission.

Our skin care routines are ever-expanding — you can find lip masks, essences, face oils, and so much more. But when you’re looking to get a potent dose of skin-loving ingredients, keep it simple with one of the best face serums.

Serums are liquid formulations that contain active ingredients to treat a number of our top skin concerns; they can soften fine lines, fade pigmentation, and zap breakouts. Serums have a thinner consistency than other skin care products like face moisturizer, but that doesn’t mean they’re not as powerful — the watery consistency actually works in your favor. That’s because a serum’s main purpose is to deliver those active ingredients deep into the skin barrier, according to board-certified cosmetic dermatologist and Mohs surgeon at the Shafer Clinic, Dendy Engelman. And the light consistency lets those ingredients seep in to help you achieve your skin goals.

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But don’t just take our word for it. More experts co-sign on incorporating serums into your routine. Along with Dr. Engelman, we asked board-certified dermatologist at MDCS Dermatology Marisa Garshick, MD, and board-certified dermatologist, associate professor and residency program director at the Loma Linda University Department of Dermatology, Janiene Luke, MD to give us a comprehensive guide to face serums for glowing skin, along with a few recommendations on which ones to use for every skin type. Ahead, our panel of pros share the best face serums for different skin types and concerns, plus tips on what to look for when you’re shopping for serums and how to apply the product.

Top Face Serums of 2023

Best for Glowing Skin

Best Vitamin C Serums

Best for Sensitive Skin

Macrene Actives High Performance Face Serum
Vichy Mineral 89 Prebiotic Recovery and Defense Concentrate
Now Foods Bakuchiol Skin Renewal Serum

Best for Dry Skin

Best for Oily Skin

Best Serums for Wrinkles

Best for Acne

Best for Hyperpigmentation

Best for Combination Skin

Drunk Elephant Protini Powerpeptide Resurf Serum
iS Clinical Active Serum
First Aid Beauty Retinol Serum 0.25% Pure Concentrate

Best Retinol Serums

Best Hyaluronic Acid Serums

Best Peptide Serums

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Best Face Serums for Glowing Skin

Costa Brazil Face Serum

Key ingredients: Vitamin C, hyaluronic acid, acai, camu camu oil, rosemary leaf oil
Size: 1 oz
Skin type: Mature, dry, combination, normal
Special features: Cruelty-free, fair trade suppliers, USDA organic ingredients
Pros: Lightweight, wears well under makeup
Cons: Subtle scent may not be for everyone

Gorgeously packaged with a silky lightweight texture, Costa Brazil’s Face Serum is a treat to use. The formula is loaded with plant-based ingredients, many of which are responsibly sourced from the Amazon. In every drop you’ll get soothing rosemary leaf oil, collagen-rich camu camu oil, and acai for a boost of vitamins A, B, C, and E.

Editor’s testing and review notes: “I simply love it,” says Mansuroglu. “It’s super lightweight and perfect to incorporate into your morning and evening skin care routine with the quality ingredients your skin needs.”

Courtesy of Costa Brazil

Costa Brazil Face Serum $135 Buy Now AT SHOPBOP

Costa Brazil Face Serum $135 Buy Now AT BLUEMERCURY

Sunday Riley Good Genes All-In-One Lactic Acid Treatment

Key ingredients: Lactic acid, arnica, aloe
Size: 1 oz
Skin type: Mature, dry, combination, oily, normal
Special features: Fragrance-free, cruelty-free
Pros: Brightens and smooths skin overnight; can be used as a serum or mask
Cons: Some reviewers experience breakouts

For glowing skin, you’ll also want to focus on ingredients that will exfoliate dead skin cells, like gentle acids. “In general, exfoliating acids can help to achieve glowing skin, as they work to eliminate dead skin cells, leaving the skin radiant and glowing,” says Dr. Garshick, who suggests looking for alpha-hydroxy acids, like glycolic or lactic acid. “Salicylic acid, a beta hydroxy acid, can be especially helpful for those with acne-prone skin.” To get glowing skin, she recommends the Sunday Riley Good Genes All-In-One Lactic Acid Treatment because it works to exfoliate skin and improve your overall complexion by sloughing away any dullness.

Editor’s testing and review notes: “Good Genes is one of the few beauty products I always have in my Dopp kit,” says Adam Mansuroglu, Director of Commerce. “It’s an essential for anyone with dry, sensitive skin — especially during the winter season.”

Courtesy of Sunday Riley

Sunday Riley Good Genes All-In-One Lactic Acid Treatment $85 Buy Now AT SEPHORA

Sunday Riley Good Genes All-In-One Lactic Acid Treatment $85 Buy Now AT ULTA

Sunday Riley Good Genes All-In-One Lactic Acid Treatment $60 Buy Now AT AMAZON

Vintner’s Daughter Active Botanical Serum

Key ingredients: 22 nutrient-rich botanicals
Size: 1 oz
Skin type: Mature, sensitive, dry, combination, oily, normal
Special features: Cruelty-free, 100% natural ingredients, fragrance-free
Pros: Provides immediate glow
Cons: Hard to detect when product is running low

A whole lot of plants are bottled up in every container of Vintner’s Daughter Active Botanical Serum. You’ll get brightening, balancing, and smoothing ingredients like avocado oil, grape seed oil, calendula, and alfalfa. It’s closer to a face oil than a serum in texture, so you can opt out of moisturizer on top.

Editor’s testing and review notes: “I can’t rave about Vintner’s Daughter Active Botanical Serum enough — the natural fragrance smells like a spa and the texture feels like silk,” says Sullivan. “When I have a bottle on hand, it’s the only product I use apart from sunscreen.”

Courtesy of Vintner’s Daughter

Vintner’s Daughter Active Botanical Serum $195 Buy Now AT NORDSTROM

Vintner’s Daughter Active Botanical Serum $195 Buy Now AT NEIMAN MARCUS

Vintner’s Daughter Active Botanical Serum $195 Buy Now AT NET-A-PORTER

Epi.Logic Master Plan Collagen Renew Growth Factor Serum

Key ingredients: Hyaluronic acid, peptides, beta glucan, snow mushroom
Size: 1 fl. oz.
Skin type: Mature, dry, combination, oily, normal
Special features: BIPOC owned, not tested on animals
Pros: Targets multiple signs of aging
Cons: Not suitable for all budgets

Epi.Logic’s Master Plan Collagen Renew Growth Factor Serum helps hydrate and firm your skin in one simple step. It was created by Brooklyn-based oculofacial plastic surgeon Dr. Chaneve Jeanniton and formulated with hyaluronic acid, peptides, and lactic acid. In addition, it includes human stem cell-derived epidermal growth factors and active proteins to promote bouncier, firmer skin.

Editor’s testing and review notes: “The Epi.Logic serum is a new staple in my skin care routine,” says senior beauty and lifestyle commerce editor Claire Sullivan. “The gel texture feels cool when I apply it, and when I apply it at night I wake up with moisturized, glowy skin.”

Epi.Logic Master Plan Serum $230 Buy Now AT Epi.Logic

Best Vitamin C Serums

Skinceuticals CE Ferulic

Key ingredients: L-ascorbic acid, vitamin E, ferulic acid
Size: 1 oz
Skin type: Mature, dry, combination, normal
Special features: Silicone-free, fragrance-free
Pros: Dark glass packaging prevents vitamin C from degrading over time
Cons: Some may find the smell off-putting

The Skinceuticals CE Ferulic is beloved in the beauty world for its instant brightening results. Its use of antioxidants is also key to getting that radiant complexion. “I love using antioxidants for an overall radiant complexion,” says Dr. Luke. “It contains potent antioxidants vitamin C and E and ferulic acid, which work synergistically to protect the skin and prevent UV-induced damage and vitamin. She adds that vitamin C “has brightening properties,” meaning that “this product can help people achieve an overall radiant glow.”

Editor’s testing and review notes: “Like many others in the beauty industry, I file this serum under holy grail status,” says Sullivan. “When I use the product consistently, I notice an improvement in my post-inflammatory erythema (aka, red spots that stick around after breakouts). But more impressively, it has a way of firming up my skin so it looks and feels healthier than ever.”

Courtesy of Skinceuticals

Skinceuticals CE Ferulic $169 Buy Now AT DERMSTORE

Skinceuticals CE Ferulic $169 Buy Now AT BLUEMERCURY

Dr. Dennis Gross Vitamin C Lactic 15% Firm & Bright Serum

Key ingredients: Lactic acid, vitamin C, licorice, alpha tocopherol
Size: 1 oz.
Skin type: Mature, dry, combination, oily, normal
Special features: Vegan, cruelty-free
Pros: Brightens, treats pigmentation, and exfoliates
Cons: The watery texture may drip off of your hands as you’re applying

Dr. Dennis Gross has a few vitamin C serums, but this one is a top choice. The brand’s Vitamin C Lactic 15% Firm & Bright Serum has immediate and long-term benefits. Lactic acid gently exfoliates skin without drying it out, and a potent form of vitamin C called L-ascorbic acid helps prevent pigmentation and fine lines from sun damage. A few drops a day will have you resurfaced and radiant.

Editor’s testing and review notes: “Dr. Dennis Gross does it again with another powerful skin care good that gets the job done,” says Mansuroglu. “After seeing immediate results from the first use, this serum become one of my winter beauty essentials.”

Courtesy of Sephora

Dr. Dennis Gross Vitamin C Lactic 15% Firm & Bright Serum $85 Buy Now AT SEPHORA

Dr. Dennis Gross Vitamin C Lactic 15% Firm & Bright Serum $85 Buy Now AT AMAZON

TruSkin Vitamin C Facial Serum

Key ingredients: Vitamin C, hyaluronic acid, vitamin E
Size: 1 oz
Skin type: Dry, combination, oily, normal
Special features: Certified cruelty-free
Pros: Inexpensive, stabilized version of vitamin C
Cons: May make your skin feel tight after application

For Dr. Engelman, vitamin C is an essential ingredient for any skin care routine. “Everyone should be using vitamin C; it’s a super-ingredient for preventing and reversing skin damage, including signs of aging,” she says. “In addition to fighting free radical damage, vitamin C improves cell turnover and helps stimulate collagen production.” This Amazon bestseller has over 87,000 five-star reviews from a range of shoppers in different age groups and with different skin types and tones. Hyaluronic acid and vitamin E deliver an immediate glow while Vitamin C works to brighten skin over time.

Courtesy of Amazon

TruSkin Vitamin C Facial Serum $22 Buy Now AT AMAZON

Best Face Serums for Sensitive Skin

Macrene Actives High Performance Face Serum

Key ingredients: Hyaluronic acid, peptides, vitamins C and E, green tea extract, resveratrol
Size: 1 oz
Skin type: Mature, sensitive, dry, combination, oily, normal
Special features: Vegan, glass packaging, USDA certified organic ingredients, fragrance-free
Pros: Calming plant-based ingredients work on all skin types
Cons: May not be suitable for all budgets

Those with sensitive skin often can’t reach for high-powered ingredients like retinol without risking irritation. With Macrene Actives High Performance Face Serum, you’ll get the firming, smoothing, and brightening benefits without any irritation. The luxurious serum feels lightweight when you apply it, so it plays well with other face creams you layer it with.

Editor’s testing and review notes: “This silky, non-greasy, lightweight formula is another winner from Dr. Macrene,” says Mansuroglu. “A little goes a long way with this luxe serum, so even though it’s not the most affordable option on the market, it’s well worth it for long-lasting results.”

Courtesy of Violet Grey

Macrene Actives High Performance Face Serum $195 Buy Now AT Sephora

Macrene Actives High Performance Face Serum $195 Buy Now AT NEIMAN MARCUS

Macrene Actives High Performance Face Serum $195 Buy Now AT NET-A-PORTER

Macrene Actives High Performance Face Serum $195 Buy Now AT VIOLET GREY

Vichy Mineral 89 Prebiotic Recovery and Defense Concentrate

Key ingredients: Niacinamide, volcanic water
Size: 1 oz
Skin type: Sensitive, dry, combination, oily, normal
Special features: Fragrance-free, allergy tested
Pros: Non-greasy and immediately calms skin
Cons: May feel sticky on some skin types

To strengthen the skin barrier, Dr. Garshick says to look for humectants, like hyaluronic acid and glycerin, as well as gentle skin brighteners, like azelaic acid. Her selection is the Vichy Mineral 89 Prebiotic Recovery and Defense Concentrate. “This serum can be used once or twice per day [and] incorporates [ingredients like] Vichy volcanic water, vitreoscilla ferment, and niacinamide, to boost the skin barrier repair and soothe the skin,” she says. “When used at night, it has been shown to reduce irritation associated with retinoid use, suggesting the benefit in those with sensitive skin.”

Editor’s testing and review notes: “This serum is one of my favorites to cycle in when I’m dealing with redness and inflammation,” says Sullivan. “I like to store it in the fridge so the gel-like texture delivers extra soothing benefits.”

Courtesy of Vichy

Vichy Mineral 89 Prebiotic Recovery and Defense Concentrate $35 Buy Now AT AMAZON

Now Foods Bakuchiol Skin Renewal Serum

Key ingredients: Bakuchiol, hyaluronic acid, squalane, green tea leaf extract
Size: 1 fl. oz.
Skin type: Sensitive, combination, oily, normal
Special features: Cruelty-free, vegan
Pros: Inexpensive, plant-based ingredients
Cons: May feel drying on dry skin types

When it comes to sensitive skin, Dr. Engelman says it’s important to find gentler alternatives. This means looking for ingredients that protect and fortify the skin barrier without causing additional irritation, like vitamin C, ceramides and niacinamide. If you’re wanting to use retinol but are a little apprehensive about potential irritation, she highly recommends the Now Foods Bakuchiol Skin Renewal Serum. “This serum is wonderful for sensitive skin,” she says. “It harnesses the power of plant-based retinol alternative bakuchiol to smooth, refine and reduce signs of aging without irritating skin.”

Courtesy of Bakuchiol

Now Foods Bakuchiol Skin Renewal Serum $13 Buy Now AT AMAZON

Best Face Serums for Dry Skin

Dr. Barbara Sturm Molecular Cosmetics Hyaluronic Acid Serum

Key ingredients: Hyaluronic acid, purslane
Size: 1 fl. oz.
Skin type: Mature, dry, combination, normal
Special features: Fragrance-free
Pros: Provides lightweight moisture,
Cons: May feel tacky on some skin types

With fans like Victoria Beckham, Hailey Bieber, and Bella Hadid, Dr. Barbara Sturm Molecular Cosmetics has a serious celebrity fan base. This Hyaluronic Serum is one of the brand’s bestsellers; it contains low and high molecular weight hyaluronic acid work to moisturize (and plump) the surface of your skin and deeper in your dermis. An ingredient called purslane helps calm irritation.

Editor’s testing and review notes: “If there’s one face serum I refuse to live without, it’s Dr. Barbara Sturm’s Hyaluronic Acid Serum,” says Mansuroglu. “I saw results in less than one month of use and the compliments kept coming from both friends and total strangers. It’s pricey but worth it.”

Courtesy of Dr. Barbara Sturm

Dr. Barbara Sturm Molecular Cosmetics Hyaluronic Acid Serum $320 Buy Now AT SEPHORA

Dr. Barbara Sturm Molecular Cosmetics Hyaluronic Acid Serum $320 Buy Now AT SAKS FIFTH AVENUE

Dr. Barbara Sturm Molecular Cosmetics Hyaluronic Acid Serum $320 Buy Now AT NORDSTROM

Dr. Barbara Sturm Molecular Cosmetics Hyaluronic Acid Serum $320 Buy Now AT SPACENK

Peter Thomas Roth Water Drench Hyaluronic Liquid Gel Cloud Serum

Key ingredients: Hyaluronic acid, silk proteins, glycerin
Size: 1 oz
Skin type: Mature, sensitive, dry, combination, normal
Special features: Fragrance-free
Pros: Provides lightweight moisture,
Cons: May feel tacky on some skin types

Peter Thomas Roth’s Water Drench line is an editor favorite for a mega dose of hydrating hyaluronic acid. In this gel formula, the ingredient is powered up with softening silk proteins and moisturizing glycerin. The gel texture leaves your skin hydrated and the semi-matte finish prevents you from feeling slick.

Editor’s testing and review notes: “I loved this gel formula so much, by the time I finished the bottle, I already ordered a second bottle,” says Mansuroglu. “If you, like I, suffer from extremely dry skin during winter, you’ll want to grab a few bottles yourself to stock up for the long cold-weather season.”

Courtesy of Peter Thomas Roth

Peter Thomas Roth Water Drench Hyaluronic Liquid Gel Cloud Serum $68 Buy Now AT AMAZON

Peter Thomas Roth Water Drench Hyaluronic Liquid Gel Cloud Serum $68 Buy Now AT ULTA

Peter Thomas Roth Water Drench Hyaluronic Liquid Gel Cloud Serum $68 Buy Now AT REVOLVE

Glow Recipe Avocado Ceramide Recovery Serum

Key ingredients: Avocado extract, ceramides, allantoin, rice milk
Size: 1 oz
Skin type: Sensitive, dry, combination, normal
Special features: Recyclable packaging, responsible ingredient sourcing, vegan formula
Pros: Emollient feel, airless pump
Cons: May feel heavy on oily skin types

Another important ingredient to banish dry skin forever are ceramides to prevent moisture loss. Dr. Garshick likes the “calming” Glow Recipe Avocado Ceramide Recovery Serum for patients with dry skin because it “works to reduce redness and supports the skin barrier without leaving the skin feeling greasy.” She adds that this serum combines ceramides with avocado extract and butter, which is rich in fatty acids, allantoin, and rice milk. “Together, they work to strengthen and moisturize the skin,” she says.

Editor’s testing and review notes: “The Glow Recipe ceramide serum feels like silk on my skin,” says Sullivan. “I love layering it under moisturizer before applying makeup.”

Courtesy of Glow Recipe

Glow Recipe Avocado Ceramide Recovery Serum Buy Now AT AMAZON

Glow Recipe Avocado Ceramide Recovery Serum $44 Buy Now AT SEPHORA

Best Face Serums for Oily Skin

Glo Skin Beauty Beta-Clarity BHA Drops

Key ingredients: Salicylic acid, retinol, glycolic acid, witch hazel
Size: 1 oz
Skin type: Oily, combination, acne-prone
Special features: Vegan, cruelty-free
Pros: Exfoliates and clears pores
Cons: Irritating if you apply too much product

The key to dealing with oily skin is balancing the skin’s barrier moisture content, says Dr. Engelman. She explains that oily skin is simply that is dry, triggering it to overcompensate and go into oil overdrive. Her pick is Glo Skin Beauty’s Beta-Clarity BHA Drops. It’s made with witch hazel, glycolic acid, retinol, and salicylic acid, which she says will help even out skin’s oil production and clarify pores.

Courtesy of Glo Skin Beauty

Glo Skin Beauty Beta-Clarity BHA Drops $54 Buy Now AT AMAZON

Glo Skin Beauty Beta-Clarity BHA Drops $54 Buy Now AT SAKS FIFTH AVENUE

The Ordinary Salicylic Acid 2% Solution

Key ingredients: Salicylic acid
Size: 1 oz
Skin type: Oily, acne-prone
Special features: Cruelty-free, vegan
Pros: Squalane-based formula helps prevent irritation
Cons: May feel drying on certain skin types

Dr. Garshick says that patients with oily skin should opt for ingredients that will reduce excess oil production, exfoliate the skin, and unclog pores. She points to The Ordinary’s Salicylic Acid 2% Solution to “help minimize irritation while decongesting pores and removing dead skin cells.” This serum was also recently relaunched with a new squalane-based formulation to further reduce any potential irritation from the salicylic acid.

Courtesy of The Ordinary

The Ordinary Salicylic Acid 2% Solution $7 Buy Now At Sephora

The Ordinary Salicylic Acid 2% Solution $6 Buy Now AT ULTA

Best Serums for Wrinkles

Augustinus Bader The Serum

Key ingredients: TFC8, vitamin C, polysaccharide complex
Size: 0.5 oz
Skin type: Mature, dry, combination, oily, sensitive
Special features: FSC certified packaging, refillable, sustainably sourced ingredients
Pros: Targets multiple signs of sun damage and aging
Cons: Expensive per ounce

The brand behind one of Jennifer Aniston’s favorite face creams also has a serum that’ll give you major skin benefits. The magic behind the formula comes from a proprietary ingredient blend called TFC8, which is designed to help your skin’s stem cells regenerate. The result is plumper, bouncier skin with less fine lines, dark spots, and dry patches.

Editor’s testing and review notes: “This is by far one of the most attractive beauty goods to have on your bathroom counter or vanity,” says Mansuroglu. “The lightweight formula provides the ideal amount of hydration during the day when combined with Augustinus Bader’s The Cream, and at night, it’s great for layering with other potent serums.”

Courtesy of Augustinus Bader

Augustinus Bader The Serum $375 Buy Now AT SEPHORA

Augustinus Bader The Serum $375 $319 Buy Now AT SAKS FIFTH AVENUE

Augustinus Bader The Serum $375 Buy Now AT BLUEMERCURY

Augustinus Bader The Serum $375 Buy Now AT NORDSTROM

SkinMedica TNS Advanced+ Serum

Key ingredients: Growth factors, peptides, flax seed, marine extracts, microalgae
Size: 1 oz
Skin type: Mature, sensitive, dry, combination, oily, normal
Special features: Fragrance-free, clinically studied
Pros: Provides visible improvements in two weeks
Cons: Dual chambers may not pump equal amounts of product when almost empty

The SkinMedica TNS Advanced+ Serum is a marvel for mature skin. The formula packs science-backed ingredients that work to soften fine lines and wrinkles, smooth your skin’s texture, and treat skin laxity. Clinical studies support the product’s efficacy, so you know it’s worth the investment.

Editor’s testing and review notes: “I just started using this powerful serum after hearing about it from a top dermatologist — and it didn’t disappoint,” says Mansuroglu. “I have been using the TNS Advanced+ Serum twice a day for almost two weeks and the results have surpassed my expectations, which says a lot considering the combination of holiday foods and alcohol I consumed for a week, along with a few days of harsh Polar Vortex winds on my skin.”

Courtesy of SkinMedica

SkinMedica TNS Advanced+ Serum $295 $236 Buy Now AT AMAZON

SkinMedica TNS Advanced+ Serum $295 $236 Buy Now AT DERMSTORE

Noble Panacea The Brilliant Prime Radiance Serum

Key ingredients: Bakuchiol, glycolic acid, malachite
Size: 30 doses
Skin type: Mature, sensitive, dry, combination, oily, normal
Special features: Cruelty-free, vegan, recycling program for used pouches
Pros: Highly potent active ingredients delivered in just-right doses
Cons: Pricey per month

The Noble Panacea The Brilliant Prime Radiance Serum has it all: Malachite, bakuchiol, glycolic acid to reveal smoother, brighter skin and protect it from future damage. Need proof? Just take a look at Jonathan Simkhai’s F/W 2022 show during NYFW. As the official skincare sponsor for Simkhai’s show, Noble Panacea provided a beauty routine including this top face serum and the Exceptional Chronobiology Sleep Mask (which was used the evening before the show) that gave the models an enviable glow as they strutted down the runway.

Noble Panacea The Brilliant Prime Radiance Serum $253 Buy Now AT NORDSTROM

Noble Panacea The Brilliant Prime Radiance Serum $253 Buy Now AT BLUEMERCURY

Best Face Serums for Acne

CeraVe Resurfacing Retinol Serum

Key ingredients: Retinol, niacinamide, ceramides
Size: 1 fl. oz.
Skin type: Sensitive, combination, oily, acne-prone, normal
Special features: Non-comedogenic, fragrance-free
Pros: Gentler than many retinols on the market
Cons: May take a few weeks to see clearing benefts

Encapsulated retinol is the magic behind Cerave’s Resurfacing Retinol Serum. The slow-release version of vitamin A gives you all the acne-fighting, pore-clearing benefits of retinol, without irritated splotches you may experience with other formulas. Ceramides help keep the skin barrier in good shape, and niacinamide brightens skin. This is a great option for those dealing with active acne or acne scars.

Courtesy of CeraVe

CeraVe Resurfacing Retinol Serum $20 Buy Now AT ULTA

Skinceuticals Silymarin CF

Key ingredients: Salicylic acid, L-ascorbic acid, ferulic acid
Size: 1 oz
Skin type: Oily, combination, acne-prone
Special features: Silicone-free, fragrance-free
Pros: Similar brightening benefits to the Skinceuticals CE Ferulic
Cons: May feel astringent once applied

Dr. Engelman explains that beta hydroxy acids (BHAs) are known to help clear acne and prevent future breakouts. Her favorite is the salicylic acid-filled serum, Silymarin CF, to prevent blemishes and breakouts. It also protects the skin from environmental aggressors.

Editor’s testing and review notes: “My combination skin loves this formula during the summer months, when I’m feeling oily,” says Sullivan. “It delivers the same benefits as CE Ferulic but in a lighter texture.”

Courtesy of Skinceuticals

Skinceuticals Silymarin CF $169 Buy Now AT DERMSTORE

Skinceuticals Silymarin CF $169 Buy Now AT BLUEMERCURY

Best Face Serums for Hyperpigmentation

U Beauty Resurfacing Compound

Key ingredients: Vitamin C and E, retinol, hyaluronic acid, alpha hydroxy acid,
Size: 1 fl. oz.
Skin type: Mature, dry, combination, oily, normal
Special features: Leaping bunny certified
Pros: Contains stabilized versions of vitamins C and retinol for max efficacy
Cons: May irritate sensitive skin types

U Beauty’s Resurfacing Compound does exactly what the name suggests — with ingredients like retinol and alpha hydroxy acids, the serum helps with cell turnover skin tone and texture. Apply the gel at night before moisturizer, and with consistent use you’ll notice a serious improvement in dark spots.

Courtesy of U Beauty

U Beauty Resurfacing Compound $148 $126 Buy Now AT SAKS FIFTH AVENUE

U Beauty Resurfacing Compound $148 Buy Now AT REVOLVE

U Beauty Resurfacing Compound $148 Buy Now AT NORDSTROM

La Roche-Posay Glycolic B5 Dark Spot Corrector

Key ingredients: Glycolic acid, tranexamic acid, kojic acid, vitamin B5
Size: 1 oz
Skin type: Sensitive, dry, combination, oily, acne-prone, normal
Special features: Fragrance-free, alcohol-free
Pros: Hydrating properties of vitamin B5 prevent dryness from exfoliating ingredients
Cons: Tricky to get product in dropper when it’s running low

Another Dr. Luke fave is the La Roche-Posay Glycolic B5 Dark Spot Corrector This gentle exfoliator will reveal smoother and brighter skin overall, due to its formula driven by glycolic acid, tranexamic acid, and vitamin B5, which together will resolve discoloration and improve skin tone. It’s also oil-, fragrance-, and alcohol-free so that it works for even the most sensitive skin.

Courtesy of La Roche Posay

La Roche-Posay Glycolic B5 Dark Spot Corrector $42 Buy Now AT ULTA

Melé Even Dark Spot Control Serum

Key ingredients: Vitamin C, niacinamide, retinol, azelaic acid, glycolic acid, kojic acid
Size: 1 oz
Skin type: Dry, combination, oily, normal
Special features: Melé partners with organizations to promote equity in the treatment of those with melanin-rich skin tones
Pros: Formulated for dark skin tones
Cons: May irritate sensitive skin types

The best ingredients to treat hyperpigmentation are vitamin C, tranexamic acid, niacinamide, azelaic acid, kojic acid, glycolic acid, cysteamine, and licorice root extract, according to Dr. Garshick. Many of these ingredients, she explains, inhibit a key enzyme in the production of melanin to treat and prevent dark spots. “The Melé Even Dark Spot Control Serum includes a combination of niacinamide, vitamin E, pro-retinol, and hydroxy resorcinol to reduce visible dark spots and discoloration,” she says.

Courtesy of Mele

Melé Even Dark Spot Control Serum $24 Buy Now AT AMAZON

Best Face Serums for Combination Skin

Drunk Elephant Protini Powerpeptide Resurf Serum

Key ingredients: Lactic acid, amino acids, snow mushroom, squalane, peptides, green tea seed oil
Size: 1 oz
Skin type: Dry, combination, oily, normal
Special features: Fragrance-free, silicone-free
Pros: Plant-based oils and squalane counteract potential irritation from lactic acid
Cons: Pump can be finicky

This exfoliating Drunk Elephant Protini Powerpeptide Resurf Serum is full of ingredients that help balance combination skin. You’ll get lactic acid to help clear out your pores in your oily areas, plus emollient ingredients like squalane and green tea seed oil to treat dry patches. You can use it at morning with SPF or at night before your favorite moisturizer.

Courtesy of Drunk Elephant

Drunk Elephant Protini Powerpeptide Resurf Serum $82 Buy Now AT SEPHORA

Drunk Elephant Protini Powerpeptide Resurf Serum $82 $62 Buy Now AT AMAZON

Drunk Elephant Protini Powerpeptide Resurf Serum $82 Buy Now AT ULTA

iS Clinical Active Serum

Key ingredients: Bilberry, mushroom extract, sugarcane extract, white willow bark
Size: 1 oz
Skin type: Mature, dry, combination, oily, normal
Special features: Fragrance-free, not tested on animals
Pros: Lightweight and cooling
Cons: May feel tingly on certain skin types

iS Clinical’s Active Serum gets high praises from dermatologists and celebs alike (Jessica Alba and January Jones love it). The formula tackles breakouts in the short term, thanks to willow bark extract. After a few months of consistent use, you’ll notice a smoother, brighter complexion with less redness, pigmentation, wrinkles, and fine lines.

Courtesy of iS Clinical

iS Clinical Active Serum $142 Buy Now AT AMAZON

iS Clinical Active Serum $142 Buy Now AT DERMSTORE

iS Clinical Active Serum $142 Buy Now AT BLUEMERCURY

First Aid Beauty Fab Skin Lab Retinol Serum 0.25% Pure Concentrate

Key ingredients: Retinol, peptides, ceramides
Size: 1 oz
Skin type: Sensitive, dry, combination, oily, normal
Special features: Cruelty-free, fragrance free, vegan
Pros: Dermatologist tested, contains a calming complex
Cons: Some shoppers report issues with the pump

“This serum combines retinol with peptides to help improve the appearance of fine lines and wrinkles,” she says of First Aid Beauty’s Retinol Serum 0.25% Pure Concentrate. “In conjunction with the Skin Saver Complex, which is made up of hyaluronic acid, colloidal oatmeal, and allantoin, it soothes the skin and minimizes irritation.”

Courtesy of First Aid Beauty

First Aid Beauty Fab Skin Lab Retinol Serum 0.25% Pure Concentrate $58 Buy Now AT SEPHORA

First Aid Beauty Fab Skin Lab Retinol Serum 0.25% Pure Concentrate $58 Buy Now AT DERMSTORE

First Aid Beauty Fab Skin Lab Retinol Serum 0.25% Pure Concentrate $58 Buy Now AT NORDSTROM

Best Retinol Serums

Joanna Vargas Super Nova Serum

Key ingredients: Retinol, apple extract, summer snowflake flower extract, persian silk tree extract
Size: 1 oz
Skin type: Mature, dry, combination, oily, normal
Special features: Vegan, cruelty-free, FSC-certified materials
Pros: Plant-based ingredients help brighten and protect skin
Cons: Contains fragrance

Joanna Vargas is a renowned aesthetician trusted by celebrities like Elisabeth Moss and Naomi Watts. Her skin care line lets you have a taste of her treatments at home, and the Super Nova Serum is a high value option to start with. The formula contains retinol to up your skin’s collagen production for a brighter, smoother complexion. You’ll also get ingredients that protect your skin from environmental aggressors like UV rays and pollution.

Courtesy of Joanna Vargas

Joanna Vargas Super Nova Serum $295 Buy Now AT AMAZON

Joanna Vargas Super Nova Serum $295 Buy Now AT DERMSTORE

Joanna Vargas Super Nova Serum $295 Buy Now AT SHOPBOP

Joanna Vargas Super Nova Serum $295 Buy Now AT VIOLET GREY

Elizabeth Arden Retinol Ceramide Capsules Line-Erasing Night Serum

Key ingredients: Ceramides, hyaluronic acid, peptides, retinol
Size: 30 to 90 capsules
Skin type: Mature, sensitive, dry, combination, normal
Special features: Biodegradable capsules
Pros: Capsules keep the product fresh and ensure the right dose of serum
Cons: May feel heavy on oily skin types

When it comes to anti-aging, Dr. Engelman recommends looking for serums with retinol to reduce fine lines. She also says that hyaluronic acid, ceramides, and peptides will help strengthen the skin’s barrier and prevent water loss. “I love these for both preventing signs of aging and helping make mature skin look and act younger,” she says of Elizabeth Arden’s Retinol Ceramide Capsules Line-Erasing Night Serum.

Editor’s testing and review notes: “These capsules are always in my travel bag — I pack enough to last me for my trip and I don’t have to worry about the mess of transferring my usual retinol into a travel container,” says Sullivan.

Courtesy of Elizabeth Arden

Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum $92 Buy Now AT ULTA

Skinbetter AlphaRet Clearing Serum

Key ingredients: Retinol, salicylic acid, lactic acid, niacinamide
Size: 1 oz
Skin type: Oily, acne-prone
Special features: Fragrance-free, cruelty-free
Pros: Effectively treats and prevents acne
Cons: Overwhelming for sensitive skin

“I love this serum because it has several ingredients that can help with oily, acne-prone skin,” says Dr. Luke of the mildly exfoliating AlphaRet clearing serum from Skinbetter. “This particular serum combines a retinoid, lactic acid, salicylic acid, and other ingredients to help control oil production.”

Courtesy of Skinbebtter

Skinbetter AlphaRet Clearing Serum $130 Buy Now At Skinbetter

Best Hyaluronic Acid Face Serums

Skinmedica HA5 Rejuvenating Hydrator

Key ingredients: Hyaluronic acid, peptide complex, vitamin E
Size: 1 oz
Skin type: Sensitive, mature, dry, combination, oily, normal
Special features: Fragrance-free, dermatologist tested, oil-free
Pros: Contains multiple types of hyaluronic acid for impressive hydrating powers
Cons: Contains silicones

“This serum blends five types of hyaluronic acid to smooth, fill in fine lines, and hydrate skin,” says Dr. Engelman of the HA5 Rejuvenating Hydrator from Skinmedica. “It provides immediate benefits and improves the appearance of skin over time, and I love Skinmedica’s proprietary Time Release HA so my skin stays hydrated all day long.”

Editor’s testing and review notes: “When I’m looking to plump my skin after a long weekend or bad night of sleep, this serum is the first thing I reach for,” says Sullivan. “It melts into my skin for instant radiance.”

Courtesy of Amazon

Skinmedica HA5 Rejuvenating Hydrator $99 Buy Now AT AMAZON

Skinmedica HA5 Rejuvenating Hydrator $99 Buy Now AT DERMSTORE

Neutrogena Hydro Boost Hydrating Serum

Key ingredients: Hyaluronic acid, glycerin
Size: 1 oz
Skin type: Dry, combination, oily, normal
Special features: Non-comedogenic
Pros: Airless pump keeps product fresh; oil-free
Cons: May pill with other serums

Hyaluronic acid is famous for its hydrating properties and ability to hold up to 1000 times its weight in water. Dr. Engelman likes the Neutrogena Hydro Boost Hydrating Serum because it utilizes hyaluronic acid to improve the moisture levels in dry skin. This gel-like, super light formula also contains other nourishing ingredients, like glycerin. As an added bonus, it’s also oil-free and non-comedogenic, meaning it won’t clog your pores.

Editor’s testing and review notes: “I recommend Neutrogena’s Hydro Boost line to anyone who’s looking for a dry skin fix on a budget,” says Sullivan. “This lightweight serum delivers results that compete with pricier serums on my vanity.”

Courtesy of Neutrogena

Neutrogena Hydro Boost Hydrating Serum $17 Buy Now AT AMAZON

Neutrogena Hydro Boost Hydrating Serum $28 Buy Now AT ULTA

La Roche-Posay Hyalu B5 Serum

Key ingredients: Hyaluronic acid, centella asiatica, vitamin B5
Size: 1 oz
Skin type: Mature, sensitive, dry, combination, oily, normal
Special features: Dermatologist and ophthalmologist tested, non-comedogenic, oil-free
Pros: Aids in treating and preventing dryness, fine lines, and irritation
Cons: Product may spill over edges of bottle

“The La Roche-Posay Hyalu B5 Serum hydrates the skin with hyaluronic acid, madecassoside, and vitamin B5, leaving it feeling soft and smooth, while also plumping it,” says Dr. Luke, who adds that you can use it by itself or used under a moisturizer for a moisture boost.

Editor’s testing and review notes: “Every time I consistently use this serum, I get major compliments on my skin,” says Sullivan. “It’s one of my all-time favorites for treating dry skin during colder months, or when I’m feeling dehydrated.”

Courtesy of La Roche Posay

La Roche Posay Hyalu B5 Serum $34 Buy Now AT AMAZON

La Roche-Posay Hyalu B5 Serum $37 Buy Now AT ULTA

Best Peptide Face Serums

PCA Ex-Linea Pro Peptide Serum

Key ingredients: Peptides, amino acids, marine extracts
Size: 1 oz
Skin type: Sensitive, mature, dry, combination, oily, normal
Special features: Dermatologist tested, fragrance-free
Pros: Firming and smoothing
Cons: May feel drying on certain skin types

Dr. Luke explains that peptides are short chains of amino acids that penetrate the skin and build important blocks of proteins — such as collagen and elastin — to maintain the skin’s structural integrity. **“**When applied topically to the skin, they act as messengers to signal the production of collagen and enhance the skin’s elasticity,” she says. She relies on the PCA Ex-Linea Pro Peptide Serum for firm and smooth skin’s texture and improve skin’s thickness.

Courtesy of PCA Ex-Linea Pro

PCA Ex-Linea Pro Peptide Serum $140 Buy Now AT AMAZON

PCA Ex-Linea Pro Peptide Serum $140 Buy Now AT DERMSTORE

PCA Ex-Linea Pro Peptide Serum $140 Buy Now AT BLUEMERCURY

Neocutis Bio Serum Firm

Key ingredients: Growth factors, peptides, sodium hyaluroniate, arginine, glycerin
Size: 1 oz
Skin type: Mature, dry, combination, oily, normal
Special features: Fragrance-free, non-comedogenic, dermatologist tested
Pros: Delivers visible improvement within 10 days of consistent use
Cons: Human growth factors may be off-putting for some

Peptides are able to penetrate the skin topically because of its small size and provide a signal to the body that healing or recovery needs to take place, according to Dr. Garshick, who says the Neocutis Bio Serum Firm provides the skin with “growth factors and proprietary peptides to improve the overall appearance of fine lines and wrinkles.” She recommends using it on the face, neck, and décolleté one to two times a day, followed by a moisturizer.

Courtesy of Neocutis Bioserum

Neocutis Bio Serum Firm $275 Buy Now AT DERMSTORE

Neocutis Bio Serum Firm $214 Buy Now AT AMAZON

Alastin Regenerating Skin Nectar

Key ingredients: Arnica extract, algae extract, flavonoids
Size: 1 oz
Skin type: Sensitive, mature, dry, combination, oily, normal
Special features: Dermatologist tested, fragrance free, non-comedogenic
Pros: Safe to use on compromised skin
Cons: Tricky to activate the pump

Dr. Engelman explains that peptides can also reduce the appearance of fine lines while reducing inflammation. She recommends the Alastin Regenerating Skin Nectar because it contains a potent combination of peptides and other actives, which amp up collagen production. It also has antioxidants and arnica montana, a soothing flower, which she says can be used on its own or after any in-office treatments to speed up the recovery.

Courtesy of Alastin

Alastin Regenerating Skin Nectar $199 Buy Now AT ALASTIN

What to Look For In the Best Face Serums

Ingredient percentage: Serums tend to contain higher percentages of active ingredients than other skin care ingredients, explains Dr. Engelman, so they are able to better target specific skin concerns. In general, serums with lower ingredient percentages will be gentler, and ones with higher percentages will be stronger. If you’re sensitive, start with the lowest available percentage to avoid irritation.
Price: Although they’re typically more expensive than other skin care staples like moisturizer and sunscreen, face serums are not a waste of money. Because these products contain a concentrated dose of ingredients, they’re investment pieces. Inexpensive serums likely include a lower quality version of the ingredient, so this is one category to splurge on. You typically only need two to three drops of serum to cover your complexion, so they’ll last you a good month or two with twice daily use.
Consistency: Lightweight options are best for max absorption into your skin. Dr. Engelman says to look for serums that have a thin, gel-like consistency, versus ones that feel oily. A watery consistency usually indicates that the formula contains molecules small enough to penetrate your skin, according to Dr. Luke.
Packaging: Some serums contain ingredients that degrade quickly when exposed to oxygen and light. Vitamin C serums are notoriously quick to oxidize, so look for options packaged in airless pumps or dark tinted glass to ensure the active ingredient retains its potency. Store your serums somewhere cool and away from sunlight, like the medicine cabinet, to keep them fresh.

The Different Types of Face Serums

Face Serums for Acne: Beta-hydroxy acids (BHAs) treat acne by clearing your pores. Look for ingredients like salicylic acid and benzoyl peroxide. For persistent acne, go with a retinoid serum. These vitamin A derivatives increase cell turnover to prevent dead cells from clogging your pores. Retinoids have the added benefit of preventing acne scars from forming, too.
Face Serums for Dull Skin: Alpha-hydroxy acids (AHAs) like lactic acid and glycolic acid deliver gentle exfoliation that will dust off dead cells to reveal a brighter, fresher-looking complexion. These serums are best used at night, as they can make your skin sensitive to sunlight. Always wear sunscreen after using an AHA.
Face Serums for Dry Skin: Hyaluronic acid serums are a great choice for boosting moisture, according to Dr. Garshick. The ingredient can hold up to 1,000 times its weight in water; apply it on slightly damp skin to quench your complexion. Glycerin is a great option, too — it helps to pull moisture into your skin.
Face Serums for Wrinkles: Retinoids to the rescue. The ingredient is the gold-standard for all things anti-aging: By increasing your skin’s collagen production, retinoids help to plump your skin from the inside out. You won’t see results overnight, but with consistent use your fine lines and wrinkles will soften.
Face Serums for Sensitive Skin: Calming ingredients are key. Look for ingredients like CBD, calendula, allantoin, and vitamin B5 to help reset your skin. Also consider gentler alternatives to retinoids and antioxidants — bakuchiol and Kakadu plum deliver similar benefits brightening and firming benefits without irritation.
Face Serums for Redness: Niacinamide is the name of the game. The ingredient reduces inflammation to quell redness — look for a low concentration to avoid irritation. You can also try plant-based ingredients like chamomile, cucumber extract, aloe, and colloidal oatmeal to calm red skin.
Face Serums for Dark Spots: You can find a number of options that help fade dark spots. Antioxidant-rich serums with ingredients like Vitamin C help your skin manage UV-induced free radicals to treat dark spots and pigmentation. You can also find ingredients like tranexamic acid that prevent pigmentation from forming — a great choice to cycle in during summertime. Niacinamide is also a powerful agent for decreasing pigmentation.

Are Face Serums Safe to Use?

Barring any skin conditions like eczema or rosacea, serums are generally safe to use (those with skin conditions should always ask their dermatologist before trying something new). If you have sensitive skin, do a patch test of the product on the inside of your forearm to see if you experience any adverse side effects like redness, flaking, or irritation.

Once you’ve followed those precautions, it’s all about choosing the right formula for your skin type and skin concerns so you don’t agitate your skin. For example, Dr. Engelman recommends that people with sensitive skin avoid irritating ingredients, such as retinol and strong alpha-hydroxy acids. Dr. Garshick adds that irritating ingredients might lead to more redness, dryness, and sensitivity, and if your serum causes even more problems (rather than reducing them), she says to discontinue use and just skip a serum altogether.

While you can combine certain serums, like hyaluronic acid and retinol, it’s best to start with just one serum at a time. This way, you’ll be able to slowly introduce the ingredient to your skin without causing irritation. Some stronger serums (like beta-hydroxy acids and retinol) shouldn’t be used at the same time. You can always check with your dermatologist if you have concerns about combining different treatments.

How To Apply Face Serum

Once you’ve picked the best face serum for your skin type and what skin concerns you want to treat, it’s important to know how to use it. A skin care routine generally has several steps to layer products based on the formula’s specific consistency. A good rule of thumb is to use your lightest products first and end with your heavier creams.

Serum is meant to be used after cleansing but before moisturizing, says Dr. Garshick. But if you have an essence or toner in your routine, she says to use those on first, followed by a serum, to ensure maximum penetration of the serum’s key ingredients.

Dr. Engelman recommends applying a serum to a damp face. Depending on the product’s packaging, you’ll pump out or use the dropper to put product into your hands and rub together to distribute product evenly then gently pat the product all around your face. She says to let it set for at least a minute before you apply other skin care products on top.

Serums can also be used at different points throughout the day, according to Dr. Garshick. She says that some products, like serums with vitamin C, are designed to protect skin during the day while others, like a retinol or acid-based serum, are more beneficial for a nighttime routine. Serums intended to calm or hydrate skin can work both during the day and night. When used at night, Dr. Garshick says you’ll wake up with healthy skin that looks and feels refreshed.

How We Chose the Best Face Serums

WWD has been at the forefront of covering the growing category of face serums for decades. For this story, we started by interviewing top dermatologists to fully understand what to look for in the best face serums. Using the dermatologists’ advice, we sought out the top serums for different skin concerns like acne, pigmentation, wrinkles, dullness, and dryness. We focused on serums with proven-ingredients like retinoids and hyaluronic acid, while also researching ingredients like tranexamic acid and Kakadu plum, which are relatively new to the skin care scene. For each skin concern, we made sure to include options to suit all skin types and skin tones. We also factored in packaging, price, and product size to include a range of options.

Meet the Experts

Dendy Engelman (MD, FACMS, FAAD): Dr. Engelman is an NYC-based, award-winning, board-certified dermatologist and Mohs surgeon at the Shafer Clinic, NYC. She also specializes in cosmetic dermatology and is known for her less-is-more approach.
Marisa Garshick (MD, FAAD): Dr. Garshick is an NYC-based board-certified dermatologist at MDCS Dermatology. She’s also an assistant clinical professor of dermatology at Cornell-New York Presbyterian Medical Center.
Janiene Luke (MD, FAAD): Dr. Luke is a California-based board-certified dermatologist and associate professor and residency program director at the Loma Linda University Department of Dermatology. She is also a leader at the Skin Of Color Society, an organization committed to educating health care providers and the general public on dermatologic health issues related to skin of color.

Meet the Author

Claire Sullivan is the Senior Beauty and Lifestyle Commerce Editor for WWD and Footwear News. She’s spent over five years researching, reporting on, and writing about the beauty industry for brands like Martha Stewart Living, Martha Stewart Weddings, InStyle, and Byrdie. She tested a number of serums on this list — she keeps La Roche Posay’s Hyalu B5 Serum and Skinceuticals CE Ferulic on standby, always. Sullivan updated this face serums story.

Audrey Noble is an NYC-based reporter who has been specializing in beauty, culture, and entertainment topics for over six years. She was previously the beauty reporter at Allure and has held an editorial position at Vanity Fair and Refinery29. Her work can also be seen in Vogue, Harper’s BAZAAR, Bustle, Martha Stewart Living, and more. Noble wrote the original version of this face serums story.

Adam Mansuroglu is the Director of Commerce for WWD and Footwear News, overseeing shopping content for both sites. The Brooklyn-native has written and edited countless fashion and beauty stories for publications such as Cosmopolitan, Men’s Health, Out Magazine and more for over 12 years. Mansuroglu contributed his testing notes to the update of this face serums guide.

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